By Richard A. Hopkins M.D. (auth.)
A significant desire of all cardiologists and surgeons concerned with the applying of allograft tissue to cardiac surgical reconstructions is met by way of this particular atlas. step-by-step, it conscientiously describes the approaches curious about buying, sterilizing, and cryo-preserving allograft valves in addition to the surgical strategy utilized in left and correct ventricular outflow tract reconstructions. all the info had to practice the reconstructions is given, together with appropriate references and appropriate adaptations in technique. very good illustrations accompany the outline of surgical approach. the entire ideas are in line with vintage techniques, yet assimilate the authors' transformations arrived at via gigantic event. The wealth of references, illustrations and services during this quantity make it a worthwhile asset for all cardiac surgeons.
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Additional resources for Cardiac Reconstructions with Allograft Valves
In addition, it has been reported l6,30 that many cell types tolerate CPA removal better at 37°C than at O°C. This increased tolerance may be related to the ability of the cells to transport solute molecules more rapidly at 37°C than at O°C. Thus the osmotic imbalances may be more quickly restored, and the cell(s) may more easily repair the damaging effects incurred by cryopreservation. Effects of Temperature on Cell Membranes Bilayer membranes are composed primarily of phospholipids, cholesterol, and proteins (glycoproteins).
London: Pitman, 1980, pp. 1-18. Karow AM Jr, Carrier 0 Jr: Effects of cryoprotectant compounds on mammalian heart muscle. Surg Gynecol Obstet 128:571, 1969. Shlafer M: Pharmacological considerations in cryopreservation. In Karow AM, Pegg DE (eds): Organ Preservation for Transplantation. 2nd Ed. New York: Marcel Dekker, 1981, pp. 177-212. Mazur P: Fundamental cryobiology and the preservation of organs by freezing. In Karow AM Jr, Pegg DE (eds): Organ Preservation for Transplantation. 2nd Ed. New York: Marcel Dekker, 1981, pp.
HOPKINS at Transplantation Techniques and Use of CryopreservedAllograJt Cardiac Valves: A Symposium and Laboratory for Surgeons. Beaver Creek, Colorado, 18-20 September 1986. Karow AM: Biophysical and chemical considerations in cryopreservation. In: Organ Preservation for Transplantation. New York: Marcel Dekker, Ed. , AM & Pegg, DE 1981, pp. 13-30. Magilligan DJ, Lewis JW, Tilley BL, Peterson E: The porcine bioprosthetic valve. J Thorac Cardiovasc Surg 89:499-507, 1985. Ross DN, Martelli V, Wain WH: Allograft and autograft valves used for aortic valve replacement.