New PDF release: Cancer Neurology in Clinical Practice 2nd Edition -

By David Schiff, Santosh Kesari, Patrick Yung Chih Wen

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Extra resources for Cancer Neurology in Clinical Practice 2nd Edition - Neurologic Complications of Cancer and Its Treatment (Current Clinical Oncology)

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Top Magn Reson Imaging 2004;15(5):279–289. 41. Dierckx RA, Martin JJ, Dobbeleir A et al. Sensitivity and specificity of thallium-201 single-photon emission tomography in the functional detection and differential diagnosis of brain tumours. Eur J Nucl Med 1994;21(7):621–633. 42. Kojima Y, Kuwana N, Noji M et al. Differentiation of malignant glioma and metastatic brain tumor by thallium-201 single-photon emission-computed tomography. Neurol Med Chir (Tokyo) 1994;34(9):588–592. 43. Griffeth LK, Rich KM, Dehdashti F et al.

46. Mavrakis AN, Halperin EF, Barker FG et al. Diagnostic evaluation of a brain mass as the presenting manifestation of cancer. Neurology 2005;65:908–911. 47. Agazzi S, Pampallona S, Pica A et al. The origin of brain metastases in patients with an undiagnosed primary tumour. Acta Neurochir (Wien) 2004;146(2):153–157. 48. Altorki N, Kent M, Pasmantier M. Detection of early-stage lung cancer: computed tomographic scan or chest radiograph? J Thorac Cardiovasc Surg 2001;121(6):1053–1057. 49. Chamberlain MC, Kormanik PA.

Although signs and symptoms are primarily confined to the cerebellar system, other areas of the nervous system may be affected, producing altered mental status, extrapyramidal signs, hearing loss, hyperreflexia, and peripheral neuropathy. In patients with SCLC, this syndrome may exist in combination with a widespread encephalomyeloneuritis. Detection of anti-Hu or anti-Yo antibodies in serum or CSF can be useful to confirm the clinical suspicion and to aid the search for a primary tumor. Over time, neuroimaging shows cerebellar atrophy, reflecting the specific loss of Purkinje cells.

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