A Practitioner's Guide to Prescribing Antiepileptics and by Jose de Leon (auth.), Jose de Leon (eds.) PDF

By Jose de Leon (auth.), Jose de Leon (eds.)

Emotional, behavioral, and neuropsychiatric stipulations are universal in people with highbrow disabilities (IDs), such a lot particularly epilepsy, aggression, self-injurious behaviors, and bipolar and different temper problems. regardless of the superiority of such difficulties, there's a shortage within the literature of trustworthy info on scientific remedies for people with IDs.

A Practitioner's consultant to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities offers an in depth framework for prescribing for this not easy inhabitants. that includes the main updated info on components that tell prescribing, the Guide addresses uncomplicated matters and controversies (e.g., the rift among evidence-based and customized medication) in treating adults with cognitive deficits. consumers' particular wishes are emphasised in constructing acceptable and powerful pharmacological intervention for more advantageous results and caliber of existence. medications mentioned within the Guide comprise carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. for every of those compounds, the ideas cover:

  • Indications to be used; relative and absolute contraindications.
  • Assessment in the course of therapy; healing drug tracking; indications and indicators for caretakers.
  • Dosage: management; preliminary and greatest steered dosage; ameliorations linked to drug-drug interactions, own features, and (where applicable) genetic variations.
  • Adverse drug reactions: universal, particularly unusual, and possibly deadly, plus possibility of metabolic syndrome.
  • Guidelines for discontinuation.
  • References, tables, and drug usage reviews.

A Practitioner's consultant to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities is an critical decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and scientific psychologists.

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Extra resources for A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities

Sample text

7). Perhaps it is obvious, then, that evidence-based approaches will never work particularly well in adult individuals with IDs, and that personalizing their treatment is even more crucial than in other areas of medicine. Few epilepsy studies are conducted in this population; although they may be included in premarketing trials, the results are not analyzed separately (Devinsky 2002). It may be impossible to develop well-controlled trials that apply to all adult individuals with IDs. To select any or several of these drugs to treat a patient, the clinician must consider many factors specific to this population: the presence (and type) or absence of epilepsy, the presence or absence of mood disorders, the presence or absence of challenging behaviors, the level of intelligence, the presence or absence of an autistic spectrum disorder, the presence or absence of any other psychiatric disorder, the presence or absence of motor or sensory deficits, and the presence or absence of a specific type of any of the hundreds of genetic abnormalities that are associated with mental retardation.

The future (or lack of future) of personalized prescription in psychiatry. Pharmacological Research, 59, 81–89. , & Singh, N. N. (2009). Practical guidelines for the use of new generation antipsychotics (except clozapine) in adult individuals with developmental disabilities. Research in Developmental Disabilities, 30, 612–669. , Susce, M. , & Murray-Carmichael, E. (2006). The AmpliChip CYP450 Genotyping Test: Integrating a new clinical tool. Molecular Diagnosis & Therapy, 10, 135–151. , & Lenotre, L.

American Journal of Mental Retardation, 94, 448–452. , & James, W. (2007). Challenging behaviours: prevalence and topographies. Journal of Intellectual Disability Research, 51, 625–636. Luchins, D. , & Dojka, D. (1989). Lithium and propranolol in aggression and self-injurious behavior in the mentally retarded. Psychopharmacology Bulletin, 25, 372–375. , & Schäuble, B. (2009). Topiramate in patients with epilepsy and intellectual disability. Epilepsy & Behavior, 14, 496–502. Matson, J. , & Rivet, T.

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